Russell E. Holzgrefe, MD

Russell E. Holzgrefe, MD

Surgery of the Hand, Orthopedic Surgery
Medical Group
Ascension Medical Group
Ascension Medical Group Ascension Medical Group
Languages Spoken


Russell Holzgrefe, MD, is an orthopedic hand surgeon with Ascension Sacred Heart Pensacola Hand Center in Pensacola, FL. Dr. Holzgrefe specializes in both surgical and non-surgical treatment of the entire upper extremity, including the hand, wrist, elbow, and shoulder. Dr. Holzgrefe aims to provide a personalized approach to patient care by listening to your concerns, understanding your goals for treatment, and then discussing your condition and treatment options.

Dr. Holzgrefe treats common hand conditions such as carpal tunnel syndrome, trigger finger, ganglion cyst, tendonitis, Dupuytren’s, and injuries of nerves and tendons. He manages fractures and broken bones of the fingers, wrist, arm, and shoulder. He treats sports injuries such as rotator cuff tears and performs arthroscopic surgery of the wrist and shoulder. Dr. Holzgrefe manages arthritis from CMC basilar thumb arthritis up to shoulder arthritis including anatomic and reverse total shoulder replacement using the latest 3D reconstruction planning and guidance technology. He has a special interest in targeted muscle reinnervation for the management of neuroma and post-amputation nerve pain.

Dr. Holzgrefe received his dual undergraduate degrees from the University of Georgia and graduated as a First Honor Graduate, Summa Cum Laude. He earned his medical degree from the University of Virginia School of Medicine in Charlottesville, VA. He completed residency training in orthopedic surgery at Emory University in Atlanta, GA and then did an extra year of subspecialty training at the University of Florida Hand and Upper Extremity Fellowship in Gainesville, FL. He has contributed to over a dozen orthopedic peer-reviewed journal articles and text book chapters and has presented research at several national meetings. Dr. Holzgrefe is a member of the American Academy of Orthopaedic Surgeons (AAOS), American Society for Surgery of the Hand (ASSH), and American Shoulder and Elbow Surgeons (ASES).
Meet Russell E. Holzgrefe, MD



  • University Of Virginia School Of Medicine


  • University of Florida Department of Orthopaedic Surgery, Hand and Upper Extremity Fellowship


  • Emory University School of Medicine, Department of Orthopedic Surgery, Orthopedic Surgery Residency


  • Emory University School of Medicine, Department of Orthopedic Surgery, Orthopedic Surgery Residency


Hospital Affiliations

  • Ascension Sacred Heart Hospital Pensacola
Professional Statement
I provide a personalized approach by listening to your concerns, understanding your goals, and then discussing the best treatment options for you.
- Russell E. Holzgrefe, MD
Why Ascension
Ascension doctors are committed to getting to know you. They take time for real back-and-forth conversations with you so they can understand all aspects of you and your life. Because great care starts with seeing your whole picture.
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